|
|
DisplayTitle
Page Content
The evolving path towards dietary guidance for bioactives.
J. W. ERDMAN (1). (1) Department of Food Science and Human Nutrition, University of Illinois, Urbana, IL, U.S.A.
It has been two decades since the Food and Nutrition Board of the US National Academy of Sciences launched its efforts to develop Dietary Reference Intakes (DRIs). From the beginning there was an intention of addressing dietary recommendations for non-essential food components within the DRI framework. This is still an unfulfilled goal. Despite considerable research progress on determining flavonoid and carotenoid content and bioavailability from foods, metabolism of these compounds and clinical trials to evaluate their bioactivity, a variety of factors have prevented development of DRIs for these bioactive classes. The current framework for DRIs is appropriate for essential nutrients but less so for food bioactive food components. The Adequate Intake (AI) and Upper Levels (UL) designations might be appropriate for bioactive or a new evaluation framework may need to be developed. There are inherent limitations in running randomize, placebo controlled, clinical trials (RCT) with high flavonoid or carotenoid-containing foods. RCTs are considered the gold standards for evidence. This presentation will review the challenges and gaps in knowledge that must be addressed before public health messages can be developed for flavonoids and non-provitamin A carotenoids. In addition, there will be a discussion of the standards and types of evidence that might be required. Lastly, the implications of not moving forward will be discussed. Many scientists feel that some accreditation of certain flavonoids and carotenoids would be most appropriate for enhancing public health.
View Presentation |
|
|
|
|
